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Chicago, Illinois–(Newsfile Corp. – February 28, 2023) – I-ON Digital Corp (OTCQB: IONI) CEO Carlos X. Montoya will participate in two exciting panel discussions at the Secure Technology Alliance’s 2023 U.S. Payments Summit on Wednesday, March 1, 2023.

This year’s conference, entitled “Innovations Abound: Exploring the new frontier of payments technologies,” will bring together hundreds of global payment leaders to provide actionable guidance for the development of next-generation payment technologies and the growing importance that identity, compliance, consent, and security play in these cutting-edge payment solutions.

Mr. Montoya will join top industry leaders to discuss current trends, innovative technologies, and the challenges of creating frictionless payment ecosystems that are secure and compliant. With Mr. Montoya’s expertise in creating regulatory-compliant fintech ecosystems, he will share insight into I-ON’s approach toward identity, cybersecurity, compliance, reporting, and consent.

“I am honored to be a part of the critical discussions being led by the Secure Technology Alliance surrounding financial industry payment settlement, now inclusive of the broader arena of healthcare payments,” said Mr. Montoya. “Topics like security, identity, and immutable reporting are essential to building trust in the payment systems and increasingly distributed data networks that connect payers, patients, and healthcare providers.”

At the event, Mr. Montoya will discuss I-ON’s Trust Framework, designed to ensure identity, cybersecurity, compliance, reporting, and consent management for digital businesses worldwide. The Trust Framework is a set of protocols and processes that help organizations verify user identity in real-time while providing secure communication and consent control measures that protect data from unauthorized access or tampering by malicious actors. It also ensures compliance with applicable regulations such as GDPR and HIPAA and allows companies to customize their consent management systems according to their needs.

“We are thrilled to have this opportunity to present our Trust Framework at the U.S. Payments Forum and share with other industry professionals how it can help increase security and transparency for digital businesses,” said Mr. Montoya. “The demand for secure digital transactions continues to grow as more businesses move online, and we believe our framework provides an invaluable solution.”

The U.S. Payments Forum is one of the premier events for payment professionals worldwide. It provides attendees with valuable insights into trends in payments technology and new solutions for consumer protection and fraud prevention strategies for merchants and financial institutions alike.

About I-ON Digital Corp
I-ON Digital Corp (the “Company”) designs, develops, and acquires technologies to deploy fully compliant, institutional-level ecosystems that fuel precious metals digitization, safe and secure wealth transfer, and data and identity sovereignty for a new generation of financial and data-driven transactions. The Company’s channels for value creation include, but are not limited to, service fees associated with asset digitization, secure transactional revenues, and the licensing of the Company’s growing intellectual property portfolio for offerings to prominent institutional organizations within the financial, healthcare, and information technology services marketplace. Additional information is available at https://iondigitalcorp.com/.

About the U.S. Payments Forum
The U.S. Payments Forum is a cross-industry body that brings stakeholders together on neutral ground to enable efficient, timely, and effective implementation of emerging and existing payment technologies. This is achieved through education, guidance, and alternative paths to adoption. The Forum is the only non-profit organization whose membership includes the whole payments ecosystem, ensuring that all stakeholders have the opportunity to coordinate, cooperate and have a voice in the future of the U.S. payments industry. The organization operates within the Secure Technology Alliance, an association that encompasses all aspects of secure digital technologies.

Forward-Looking Statements
This news release contains forward-looking statements that involve risks and uncertainties, which may cause actual results to differ materially from the statements made. When used in this document, the words “may,” “would,” “could,” “will,” “intend,” “look to,” plan,” “anticipate,” “believe,” “estimate,” “expect,” “seek,” “potential,” “outlook,” and similar expressions are intended to identify forward-looking statements. Such statements, including, but not limited to, I-ON’s current views with respect to future events and its financial forecasts, are subject to such risks and uncertainties. Many factors could cause actual results to differ materially from the statements made, including those risks described from time to time in filings made by I-ON with the Securities and Exchange Commission. In addition, there is uncertainty about the further spread of the COVID-19 virus or new variants thereof, or the occurrence of another wave of cases and the impact it may have on the Company’s operations, the demand for the Company’s products, global supply chains and economic activity in general. These and other risks and uncertainties are detailed in the Company’s filings with the Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results may vary materially from those described herein as intended, planned, anticipated or expected. Statements in this news release regarding past trends or activities should not be taken as a representation that such trends or activities will continue. I-ON does not intend and does not assume any obligation to update these forward-looking statements, other than as required by law.

SOURCE: I-ON Digital Corp

Media Contact:
Ken Park
IR@iondigitalcorp.com

(866) 440-2278
www.iondigitalcorp.com

EDISON, N.J., Feb. 27, 2023 (GLOBE NEWSWIRE) — Zerify Inc. (OTCPINK: ZRFY), the 21-year-old cybersecurity company focused on securing digital communications, announced today that Small-to-Medium sized business are turning to Zerify to protect confidential corporate & client data.

“SMBs are under attack,” says Mark L. Kay, CEO of Zerify. “We are honored that they are signing up to use our Zerify Meet™ Secure Video Conferencing and Zerify Defender™ secure desktop solutions. Given the fact that most SMBs don’t have an experienced cybersecurity team on staff to help navigate critical security & compliance requirements, we are thrilled that they are turning to Zerify to help them protect their corporate & client data.”

On Dec. 16^th 2022, the FBI reported that Small-to-Medium sized businesses face a big threat from cyberattacks and hackers. “This is a great opportunity for Zerify,” says Kay, “because hackers are easily bypassing existing anti-virus and Endpoint Detection & Response (EDR) systems and are going after voice, video, and audio communications, which is part of every company’s digital communications ecosystem. Zerify is the only company on the market that has a proactive solution that locks down your camera, microphone, speakers, keyboard, clipboard, and prevents screenscraping malware.”

“Computers, applications & mobile devices are all components that make-up a company’s digital communications ecosystem, therefore, protecting those from malware should be a top concern for every business leader,” says Kay. “That’s why we are very pleased to share below three Zerify’s SMB business leaders and why they choose to use our solutions.”:

• Loy C. (Transformation Visionary Educator for the Americas, Asia and Africa), as a visionary entrepreneur and mentor with contacts throughout the world, said, “I was looking for a video conferencing platform that was secure and reliable. I’ve been using Zerify for about a year now and have found their security features far superior compared to others offering similar services. Having a background in Management of Information Systems myself, I was impressed with their camera and keyboard security for the host and multiple authentication options. No company out there is offering this level of security features, Impressive! In addition, they offer features and services that are scalable as my business grows with price points that are reasonable and relevant. Lastly, a real person responds to any technical questions promptly that you may have, which is refreshing in this age of AI, bots and outsourcing customer service!”
• Richard Bruce Paschal (Attorney) said, “I have been a practicing attorney for 40 years, as a transactional and successful civil trial attorney. I spent many years as a defense attorney in professional malpractice actions involving CPAs, engineers and accountants. I also represented clients in construction defect cases and business litigation cases. I am a former director and general counsel of a 100-plus employee engineering company in the San Francisco Bay Area and held those positions for over 7 years. Protecting Intellectual property & client data is essential to my business, that’s why I choose to use Zerify’s solutions. They secure my business, they are easy to use, and very affordable. I would recommend them to any business that needs to secure corporate & client data.”
• John Wachter (Owner Operator of Sunburnt Cottages) said, “We specialize in arranging the perfect cottage experience, or island getaway for vacationers. Since we deal with a lot of personal information we needed to get the most secure solution to protect our clients data, that’s why we choose to utilize Zerify’s solutions, they help us keep our clients information secure.”

“We love working with SMBs,” says Kay, “they are the backbone of the country, we treat each of our customers as if they are our most important customer, because each of them is. We don’t require any long term contracts, our software is licensed month-to-month, and we even offer a 14-day free trial on our website. We look forward to making each of you our most important customer,” says Kay.

To learn more about Zerify solutions, go to: https://www.zerify.com/

About Zerify
Zerify Inc. (OTC: ZRFY), formerly StrikeForce Technologies, is an Edison, New Jersey-based company with over two decades of experience in cybersecurity solutions. The company helps to prevent cyber theft and data security breaches for consumers, corporations and government agencies through powerful multi-factor “out-of-band” authentication and keystroke encryption along with mobile solutions. Zerify offers a video conferencing solution that uses no desktop and is entirely web-based, offering a five-level meeting security control approach designed to protect valuable information. Features include keystroke protection, anti-screen capture, and push and biometric authentication to keep businesses secure. The technology also protects cameras, microphones and speakers, keeping computers and confidential data secure even when one is offline and not on a video conference. No other video conferencing service on the market, such as Zoom, Webex, LogMeIn, MS Teams or BlueJeans, offers these protections.

Zerify Contact:
Mark L. Kay
marklkay@zerify.com
(732) 661-9641

WEST PALM BEACH, Fla., Feb. 22, 2023 (GLOBE NEWSWIRE) — RennovaHealth, Inc. (OTC: RNVA) Chief Executive Officer Seamus Lagan recently joined Stock Day host Everett Jolly to provide an update on 2022 financial statements and other activities.

Jolly began the interview by referring to the improved previous quarterly reports and asked if the Company could provide an update on the 2022 financial statements that are soon due for filing. Lagan responded by confirming that filings would be made on time and would show a continued improvement in revenues and profitability for the 4th quarter and a significant improvement from previous years.

Jolly asked for an update on the behavioral health division. Lagan confirmed that in anticipation of opening, a new web site describing the services has been launched at www.myrtlerecoverycenters.com He confirmed that relevant license applications for medically supervised withdrawal, residential recovery and OBOT services had been submitted and were expected in the near future. He also confirmed that building and decorating works including furnishing will be completed in the coming weeks with the facility expected to be ready for patients at the end of March. Opening is predicted to be in the 2^nd quarter of 2023 subject to staffing and licensure.

Jolly then asked if the company had plans to reopen its closed facility or plans to look for additional acquisitions. Lagan stated that the priority was to ensure continued consistency with the current operations and to get the behavioral health facility opened in the second quarter as planned but then explained that consideration would be given to adding behavioral health services at the Jamestown facility and reopening a hospital operation similar in size to the current Big South Fork operations. Lagan also confirmed that the Company was very open to an acquisition strategy to expedite growth.

Jolly ended the interview by asking Lagan what message he would like the Company’s shareholders to take away from the interview. Lagan responded by saying that despite certain hurdles and challenges remaining he believed the Company could continue with its current rate of improvement and create opportunity for shareholders and investors.

To hear Seamus Lagan’s entire interview, follow the link to the podcast here:

Stock Day Media / Rennova Health (RNVA) is Featured on The Stock Day Podcast (audioboom.com)

Investors Hangout is a proud sponsor of “Stock Day,” and Stock Day Media encourages listeners to visit the company’s message board at https://investorshangout.com/

About Rennova Health, Inc.
Rennova Health, Inc. (“Rennova,” the “Company,” “we”, “us”, “its” or “our”) is a provider of health care services. The Company owns one operating hospital in Oneida, Tennessee known as Big South Fork Medical Center, a hospital located in Jamestown, Tennessee that it plans to reopen, a physician’s practice in Jamestown, Tennessee that it plans to reopen and a rural clinic in Kentucky. For more information, please visit www.rennovahealth.com

Forward-Looking Statements
This press release includes “forward-looking statements” within the meaning of the safe harbor provisions of the United States Private Securities Litigation Reform Act of 1995. Actual results may differ from expectations and, consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions are intended to identify such forward-looking statements. These forward-looking statements involve significant risks and uncertainties that could cause the actual results to differ materially from the expected results. Additional information concerning these and other risk factors are contained in the Company’s most recent filings with the Securities and Exchange Commission. The Company cautions readers not to place undue reliance upon any forward-looking statements, which speak only as of the date made. The Company does not undertake or accept any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements to reflect any change in their expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law.

Contact:

Rennova Health
561-855-1626
info@rennovahealth.com

Chicago, Illinois–(Newsfile Corp. – February 22, 2023) – I-ON Digital Corp (OTCQB: IONI) is proud to announce that its new management team will attend a series of industry events over the next several weeks with the goal of introducing new enhancements to the industry’s first institutional-level Gold-Backed Digital Asset Ecosystem, as well as the Company’s upcoming launch of its ION Digital Trust Framework inside the financial services and healthcare industries.

The first event on I-ON’s schedule is the strategic Mines and Money Investor Conference, occurring February 23-24 in Miami, Florida. This event is designed to help investors identify investment opportunities and gain insights into current market trends, focusing on metals and mining. I-ON will showcase groundbreaking enhancements being made to the original Gold-Backed Digital Asset Ecosystem Mr. Montoya engineered in early 2017. The Company expects that I-ON’s gold digitization process will allow investments in gold-backed digital securities backed by unrefined gold reserves held in the planet’s most secure vault – Mother Earth.

“We’ve been very heavily focused on expanding what had originally been developed by our initial team members at MCM and Tall Ship Partners Fund in 2017 when we launched the world’s first institutional-level ecosystem,” said I-ON Digital Corp CEO Carlos X. Montoya. “With the introduction of ION’s Digital Trust Framework, we will look to add precious metals to our digitization process. We expect to enhance proof of reserve protocols, strengthen independent financial custody, expand tier-one client and investor reporting, and streamline account management using Blockchain and Smart Contract technologies.”

Following this event, I-ON will be attending U.S. Payments Forum on February 27-March 2 in Salt Lake City, Utah. This conference focuses on payment solutions and trends within the financial services industry. During this time, the ION team will highlight their Trust Framework technology, which utilizes blockchain technology and workflow automation to create an immutable audit trail for payment transactions while maintaining customer identity, privacy, and data security standards required by law.

“The ION Trust Framework was engineered to further protect consumer identity, facilitate secure and compliant wealth transfer, and strengthen individual data sovereignty protection as a top priority,” said Montoya. “The concept of Distributed Trust is an essential and much-needed solution for financial and data transactions worldwide to ensure compliance with emerging international identity, consent, and transmission standards, and we believe it has great potential not only in the traditional finance sector but also in other industries such as healthcare.”

These two upcoming events offer an exciting opportunity for I-ON to demonstrate its technological capabilities further and strengthen relationships with its industry partners worldwide.

About I-ON Digital Corp
I-ON Digital Corp (the “Company”) designs, develops, and acquires technologies used to deploy fully compliant, institutional-level ecosystems that fuel precious metals digitization, safe and secure wealth transfer, and data and identity sovereignty for a new generation of financial and data-driven transactions. The Company’s channels for value creation include, but are not limited to, service fees associated with asset digitization, secure transactional revenues, and the licensing of the Company’s growing intellectual property portfolio for offerings to prominent institutional organizations within the financial, healthcare, and information technology services marketplace. Additional information is available at https://iondigitalcorp.com/.

About Mines and Money
Mines and Money is the leading international event series connecting sophisticated investors worldwide with mining company management teams online and in person. With an unrivaled network of thousands of international investors, our events are the place where professional investors meet exciting explorers on the cusp of the next big discovery, near-production development companies, and cash-generative producers to discuss their next big mining investment.

Senior management teams of mining companies can connect with institutional and private investors worldwide at Mines and Money events. Our online meetings platform will help you to schedule lucrative meetings so you can provide project updates, share presentations, and discuss with pre-qualified investors why they should invest in your Company.

About the U.S. Payments Forum
The U.S. Payments Forum is a cross-industry body that brings stakeholders together on neutral ground to enable efficient, timely, and effective implementation of emerging and existing payment technologies. This is achieved through education, guidance, and alternative paths to adoption. The Forum is the only non-profit organization whose membership includes the whole payments ecosystem, ensuring that all stakeholders have the opportunity to coordinate, cooperate and have a voice in the future of the U.S. payments industry. The organization operates within the Secure Technology Alliance, an association that encompasses all aspects of secure digital technologies.

Forward-Looking Statements
This news release contains forward-looking statements that involve risks and uncertainties, which may cause actual results to differ materially from the statements made. When used in this document, the words “may,” “would,” “could,” “will,” “intend,” “look to,” plan,” “anticipate,” “believe,” “estimate,” “expect,” “seek,” “potential,” “outlook,” and similar expressions are intended to identify forward-looking statements. Such statements, including, but not limited to, I-ON’s current views with respect to future events and its financial forecasts, are subject to such risks and uncertainties. Many factors could cause actual results to differ materially from the statements made, including those risks described from time to time in filings made by I-ON with the Securities and Exchange Commission. In addition, there is uncertainty about the further spread of the COVID-19 virus or new variants thereof, or the occurrence of another wave of cases and the impact it may have on the Company’s operations, the demand for the Company’s products, global supply chains and economic activity in general. These and other risks and uncertainties are detailed in the Company’s filings with the Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results may vary materially from those described herein as intended, planned, anticipated or expected. Statements in this news release regarding past trends or activities should not be taken as a representation that such trends or activities will continue. I-ON does not intend and does not assume any obligation to update these forward-looking statements, other than as required by law.

SOURCE: I-ON Digital Corp

Media Contact:
Ken Park
IR@iondigitalcorp.com

(866) 440-2278
www.iondigitalcorp.com

LOS ANGELES, CA, Feb. 21, 2023 (GLOBE NEWSWIRE) — via NewMediaWire — Recent derailment of the train carrying hazardous chemicals in East Palestine, Ohio highlights the severe dangers posed from chemical spills or attacks, and how important it is to be able to quickly identify dangerous chemicals in the air, food, or water, and protect yourself and your community from them. US Nuclear (OTC-QB: UCLE) specializes in hazardous material detection and is helping to preserve the life and health of first responders, workmen and by-passers making people more secure and better prepared through use of their unique drone-mounted and hand-held hazardous chemical detectors. When a first responder sends one of US Nuclear’s fully instrumented drones directly into the danger zone he saves himself from the risk of potentially fatal exposure. Whether accidental or malicious, toxic spills or explosions need to be dealt with.

In the event of a chemical spill, attack, or fire, first responders, healthcare departments, emergency response, environmental agencies, and local residents all need the ability to quickly and accurately identify what and where the chemicals are so they can help mitigate or prevent dangerous exposure. The key to staying safe is being prepared and having the right equipment in the event of an emergency.

US Nuclear is now offering airborne chemical detectors utilizing unique open-loop ion mobility spectrometry (IMS) for chemical detection and identification. A real-time trend display allows for hazardous chemical surveillance, warning for areas with higher concentrations of chemicals before it even reaches the alarm level, and sharing the real-time data, location, and alarms with other team members or a central command station. Two versions are currently available, drone-mounted or hand-held:

DroneCHEM-2-IWC: Drone-mounted version

DroneCHEM-2-IWC-H: Hand-held version

In addition, US Nuclear also offers novel miniature mass spectrometers that can also be mounted on UAVs to detect war gases, industrial chemicals, nerve gases and poisons, irritants, explosives, drugs, and hazardous chemicals. US Nuclear’s drones are the perfect tool for surveying hazardous sites safely, and can be equipped with numerous sensor payloads depending on the job at hand.

Safe Harbor Act

This press release includes “forward-looking statements” within the meaning of the safe harbor provisions of the United States Private Securities Litigation Reform Act of 1995. Actual results may differ from expectations, estimates and projections and, consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions are intended to identify such forward-looking statements. These forward-looking statements involve significant risks and uncertainties that could cause the actual results to differ materially from the expected results.

Investors may find additional information regarding US Nuclear Corp. at the SEC website at http://www.sec.gov, or the company’s website at www.usnuclearcorp.com

CONTACT:

US Nuclear Corp. (OTC-QB: UCLE)
Robert I. Goldstein, President, CEO, and Chairman
Richard Landry, Chief Financial Officer
(818) 883 7043
Email: info@usnuclearcorp.com
http://usnuclearcorp.com
http://tech-associates.com
http://overhoff.com

Phoenix, Arizona–(Newsfile Corp. – February 6, 2023) – The Stock Day Podcast welcomed US Nuclear Corp. (OTCQB: UCLE) (“the Company”), a radiation, chemical detection and specialty drone, holding company specializing in the development and manufacturing and sales of radiation and chemical detection instrumentation. CEO of the Company, Bob Goldstein, joined Stock Day host Everett Jolly.

“How are your sales recovering from COVID?” asked Jolly. “They are definitely turning around,” said Goldstein. “We have a loyal customer base,” he added. “Our US overseas representatives kept us going during that period, but now that we are able to travel safely we are going to bring back the trade shows.”

“Do you get a lot of traction from the trade shows?” asked Jolly. “Yes,” shared Goldstein. “Trade shows are great because sales is all about relationships and at the shows you are face-to-face and are able to discuss a customer’s specific needs,” he explained. “There is even the opportunity to demo your products and answer questions, while hopefully setting up for a secure sale.”

“How many trade shows do you think you will attend in 2023?” asked Jolly. “We were doing about six to ten trade shows per year previously,” said Goldstein. “We already have four shows set up for the first half of 2023,” he added, noting that the Company will be attending its first show on February 19th at the Indoor Air Quality Show in Austin, Texas. “On April 18th, there is a Water Quality Association Show in Las Vegas, Nevada,” he shared. “On March 20th, we have the International Air, Soil, Water, and Energy International Show in San Diego, California, followed by Down stream USA Oil and Gas conference in Galveston Texas.”

The conversation then turned to the Company’s PFAS protection technology. “It is such a huge problem; by now we all have plastic in our veins,” said Goldstein. “We are offering a PFAS/PFOS detector that can indicate the presence of these chemicals in the water or air within a few minutes, where typically you would have to take your sample to a lab and wait two weeks,” he explained. “So, I believe we have the opportunity for significant product sales coming to us.”

“What are the products you will be showcasing at the trade shows this year?” asked Jolly. “We have universal detection systems that can detect not just radiation, which is our specialty, but also a wide range of very dangerous chemicals including explosives, biological toxins and even fentanyl,” said Goldstein, before elaborating on the significance of the applications for these technologies.

Goldstein then discussed the potential of the Company’s return to trade shows across 2023, and encouraged listeners and shareholders to keep up-to-date on their upcoming announcements and projects.

To hear Bob Goldstein’s entire interview, follow the link to the podcast here: https://audioboom.com/posts/8242632-us-nuclear-corp-discusses-2023-trade-show-schedule-with-the-stock-day-podcast.

Investors Hangout is a proud sponsor of “Stock Day,” and Stock Day Media encourages listeners to visit the company’s message board at https://investorshangout.com/.

About US Nuclear Corp.

US Nuclear Corp is a radiation, chemical detection and specialty drone, holding company specializing in the development and manufacturing and sales of radiation and chemical detection instrumentation. Through its four operating divisions (Technical Associates (TA), Overhoff Technology (OTC), Electronic Control Concepts (ECC), and Cali From Above (CFA), US Nuclear Corp. harbors more than 100 years of combined experience in supplying top of the line instrumentation to any industry utilizing radionuclides. This includes nuclear power plants, national laboratories, government agencies, homeland security, military, universities and schools, research companies, hospitals, medical and dental centers, energy companies, weapons facilities, first responders, local governments, and manufacturing plants.

Safe Harbor Act

This press release includes “forward-looking statements” within the meaning of the safe harbor provisions of the United States Private Securities Litigation Reform Act of 1995. Actual results may differ from expectations, estimates and projections and, consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions are intended to identify such forward-looking statements. These forward-looking statements involve significant risks and uncertainties that could cause the actual results to differ materially from the expected results.

Investors may find additional information regarding US Nuclear Corp. at the SEC website at http://www.sec.gov, or the company’s website at www.usnuclearcorp.com.

CONTACT:

US Nuclear Corp. (OTCQB: UCLE)
Robert I. Goldstein, President, CEO, and Chairman
Richard Landry, Chief Financial Officer
(818) 883 7043
Email: info@usnuclearcorp.com
Usnuclearcorp.com

About The “Stock Day” Podcast

Founded in 2013, Stock Day is the fastest growing media outlet for Nano-Cap and Micro-Cap companies. It educates investors while simultaneously working with penny stock and OTC companies, providing transparency and clarification of under-valued, under-sold Micro-Cap stocks of the market. Stock Day provides companies with customized solutions to their news distribution in both national and international media outlets. The Stock Day Podcast is the number one radio show of its kind in America.

SOURCE:

Stock Day Media
(602) 821-1102

Phoenix, Arizona–(Newsfile Corp. – January 25, 2023) – The Stock Day Podcast welcomed Trevi Therapeutics, Inc. (NASDAQ: TRVI) (“the Company”), a clinical-stage biopharmaceutical company developing the investigational oral therapy Haduvio™ (nalbuphine ER) for the treatment of chronic cough in adults with IPF, other chronic cough indications, and for the treatment of prurigo nodularis. President and CEO of the Company, Jennifer Good, joined Stock Day host Everett Jolly.

Jolly began the interview by asking about the Company’s background and current projects. “We started this company back in 2010 to explore the broad mechanism around a drug called nalbuphine ER,” shared Good, adding that she is also one of the Co-Founders of the Company. “We have been looking at difficult to treat conditions that all have some interconnectivity,” she explained. “Our path forward here is through severe chronic cough, which is also linked to some tough diseases.”

Jolly then asked for an update on the Company’s Phase 2 CANAL trial of its investigational oral therapy Haduvio™ in chronic cough in IPF. “IPF is a progressive fibrotic lung disease, which typically has a mortality rate of 3-5 years,” Good explained. “One of the biggest complaints of this disease is chronic coughing,” she added. “We are trying to settle down the coughing, which may in return impact the underlying disease,” she said. “This was a proof-of-concept trial in which we reported full results in September, and the data was significantly positive.”

“We had a response to the drug with about a 75% reduction of the cough over three weeks, which is a tremendous impact,” continued Good. “That was exciting for us, and there was nothing new found on the safety side,” she shared. “We are now moving forward with cough as our main focus,” said Good. “We were also able to raise money, so we now have plenty of cash to execute these next phases of development.”

“What do you have planned for this year in terms of clinical trials?”, asked Jolly. “It will be a very busy year for us clinically,” said Good, adding that 2022 was a significant year for the Company in terms of de-risking their oral therapy. “We have enough cash to take us into 2026,” she shared. “This year, we are going to do a dose-ranging study,” said Good. “It will be with roughly 200 patients, 50 per our three dosage strengths and a placebo, and we plan to start that in the second quarter of this year,” explained Good. “In parallel to that, we are also going to run a Phase 1B safety study.”

“We will also plan to initiate a refractory chronic cough study, which is a big market and a different cough indication,” continued Good, before elaborating on the significance and potential of this study. “This will be a crossover study and we plan to start that in the third quarter of this year.”

Jolly then asked about the Company’s recent addition of Dr. David Clark as their Chief Medical Officer. “David has a strong respiratory background, which is quite relevant as we work our way through our cough program,” said Good. “He also has a history of working as a CMO for companies doing rare disease work,” she added. “David has had a lot of success at designing key trials that have been game changing for their companies. In fact, two of his companies have been acquired for healthy premiums.”

To close the interview, Good elaborated on the Company’s potential as they continue to develop and de-risk their chronic cough indication. “I think we are well positioned now to get this out to a broader market,” said Good. She also encouraged listeners and shareholders to keep up-to-date on the Company’s upcoming announcements and current projects as they continue to progress clinically.

To hear Jennifer Good’s entire interview, follow the link to the podcast here: https://audioboom.com/posts/8235624-trevi-therapeutics-inc-discusses-progress-and-2022-success-of-clinical-studies-for-its-investig

Investors Hangout is a proud sponsor of “Stock Day,” and Stock Day Media encourages listeners to visit the company’s message board at https://investorshangout.com/

About Trevi Therapeutics, Inc.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational oral therapy Haduvio™ (nalbuphine ER) for the treatment of chronic cough in adults with IPF, other chronic cough indications, and for the treatment of prurigo nodularis. The Company reported statistically significant results from the Phase 2 CANAL trial of Haduvio for the treatment of chronic cough in adults with IPF. Based on this positive data, Trevi plans to focus future clinical development on chronic cough conditions, including IPF, refractory chronic cough, and interstitial lung diseases (ILDs).

For more information, visit www.TreviTherapeutics.com and follow the Company on Twitter and LinkedIn.

About Haduvio

Haduvio, an investigational therapy, is an oral extended-release (ER) formulation of nalbuphine. Nalbuphine is a mixed ĸ-opioid receptor agonist and µ-opioid receptor antagonist that has been approved and marketed as an injectable for pain indications for more than 20 years in the United States and Europe. The ĸ- and µ-opioid receptors are centrally and peripherally active and known to be critical mediators of cough and itch. Nalbuphine’s mechanism of action may also mitigate the risk of abuse associated with µ-opioid agonists because it antagonizes, or blocks, µ-opioid receptors. Parenteral nalbuphine is not currently scheduled as a controlled substance by the DEA in the United States or by regulatory authorities in most of Europe. Trevi intends to propose Haduvio as the trade name for nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements are subject to risks and uncertainties and actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding Trevi’s business plans and objectives, including future plans or expectations for Haduvio and plans with respect to future clinical trials, and other statements containing the words “believes,” “anticipates,” “plans,” “expects,” and similar expressions. Risks that contribute to the uncertain nature of the forward-looking statements include: uncertainties regarding the success, cost and timing of Trevi’s product candidate development activities and ongoing and planned clinical trials; the risk that positive data from a clinical trial may not necessarily be predictive of the results of future clinical trials in the same or a different indication; uncertainties regarding Trevi’s ability to execute on its strategy; uncertainties with respect to regulatory authorities’ views as to the data from Trevi’s clinical trials and next steps in the development path for Haduvio in the United States and foreign countries; as well as other risks and uncertainties set forth in the quarterly report on Form 10-Q for the quarter ended September 30, 2022 filed with the Securities and Exchange Commission and in subsequent filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Trevi undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Investor Contact

Katie McManus
Trevi Therapeutics, Inc.
203-304-2499
k.mcmanus@trevitherapeutics.com

Media Contact

Rosalia Scampoli
914-815-1465
rscampoli@marketcompr.com

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